Insider purchases are often scrutinized by investors as they can offer insights into a company's long-term prospects. Insiders, such as company officers, directors, and significant shareholders, typically have access to valuable internal information and are subject to strict rules regarding their trades. 

Recently, notable insider activity has been observed in large-cap companies like FedEx, Casey's General Stores, and Centene. For instance, FedEx's CFO purchased 1,000 shares, a transaction totaling nearly $275,000, reflecting confidence despite the company's recent underperformance. 

Casey's General Stores saw a director buy 500 shares worth almost $200,000, showing strong support as the stock outperforms the S&P 500. Meanwhile, Centene saw several insiders invest roughly $1.6 million, although analysts remain cautious about its near-term outlook due to recent struggles.

Finsum: This could be a critical time to invest in large cap because macro factors could be pointing their direction.